BDBM50376421 CHEMBL410426

SMILES Cc1cc(-c2ccc(\C=C3\C(=O)NN(C3=O)c3cccc(Cl)c3)o2)c(cc1C)[N+]([O-])=O

InChI Key InChIKey=OOPIEWKXPZBABX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376421   

TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50: 8.95E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50: 8.55E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed