BDBM50376417 CHEMBL261865

SMILES [O-][N+](=O)c1ccc(COc2ccc(Cl)cc2C=C2C(=O)NC(=O)N(C2=O)c2ccccc2F)cc1

InChI Key InChIKey=XGAPMFLSMNOPPE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50376417   

TargetCoagulation factor VIII(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human factor 8 binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50: 3.81E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor V(Human)
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed