BDBM50376365 CHEMBL259394

SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4)cc3F)c2cc1OC

InChI Key InChIKey=DNLCCAYVZKRIEN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376365   

TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50376365(CHEMBL259394)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGFR expressed in DHER14 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50376365(CHEMBL259394)
Affinity DataIC50: 500nMAssay Description:Inhibition of Her2 expressed in CSH12 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50376365(CHEMBL259394)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IGF1R by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed