BDBM50376043 CHEMBL272449

SMILES COc1cc2ncc(F)c(Oc3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC

InChI Key InChIKey=TVAPQTUGLKOYAA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376043   

TargetVascular endothelial growth factor receptor 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50376043(CHEMBL272449)Copy SMILESCopy InChI

Affinity DataIC50: 20nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/15/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetVascular endothelial growth factor receptor 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50376043(CHEMBL272449)Copy SMILESCopy InChI

Affinity DataIC50: 19.9nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/22/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL