BDBM50376002 CHEMBL411284

SMILES COc1cc2ncnc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC

InChI Key InChIKey=JLBAXNKYJZOYGQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50376002   

TargetAurora kinase B(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 360nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50376002(CHEMBL411284)
Affinity DataIC50: 2.88nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed