BDBM50375299 CHEMBL258458

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2o1

InChI Key InChIKey=JBEVAWMNEBELDV-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375299   

TargetMu-type opioid receptor(Guinea pig)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375299(CHEMBL258458)
Affinity DataIC50: 170nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-stimulated Hartely guinea pig contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375299(CHEMBL258458)
Affinity DataKi:  0.283nMAssay Description:Binding affinity to delta opioid receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375299(CHEMBL258458)
Affinity DataKi:  1.42nMAssay Description:Binding affinity to mu opioid receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed