BDBM50374845 CHEMBL256271

SMILES CC1CC(CCN1S(=O)(=O)c1ccccc1Cl)N1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=MMWTVPRHOYOBHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374845   

TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50374845(CHEMBL256271)
Affinity DataIC50: 320nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50374845(CHEMBL256271)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed