BDBM50374837 CHEMBL403728

SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Br)c1ccc(Cl)cc1

InChI Key InChIKey=GEIKHQRXCHGMAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374837   

TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50374837(CHEMBL403728)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50374837(CHEMBL403728)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed