BDBM50373858 CHEMBL255170

SMILES Cc1ccc(Oc2ccc(Nc3ncnc4n[nH]c(OCCN5CCC(O)CC5)c34)cc2Cl)cn1

InChI Key InChIKey=UWUFUUGZSOQBCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373858   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50373858(CHEMBL255170)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50373858(CHEMBL255170)
Affinity DataIC50: 184nMAssay Description:Inhibition of erB2 autophosphorylation in clone 24 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed