BDBM50373826 CHEMBL256470

SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ncnc2c(C)csc12

InChI Key InChIKey=BPRNMVDTWIHULJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50373826   

TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 5(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at LPA5 receptor in human isolated platelets assessed as inhibition of hexadecyl-LPA-induced platelet aggregation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed