BDBM50373776 CHEMBL256203

SMILES O=C(Nc1cc(cn(CC2CC2)c1=O)-c1ccccc1)N1CCC(CC1)n1cc([nH]c1=O)-c1ccccc1

InChI Key InChIKey=WBEZWDQPJDHRFH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373776   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373776(CHEMBL256203)
Affinity DataIC50: 360nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373776(CHEMBL256203)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]CGRP from human recombinant CL receptor /RAMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed