BDBM50373474 CHEMBL402769

SMILES CC[C@H](NC(C)=O)c1cc(Cl)ccc1C1CCN(CC1)C(=O)[C@H]1CN(C[C@@H]1c1ccc(cc1)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=PNFDTYPRKXTXAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50373474   

TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373474(CHEMBL402769)
Affinity DataIC50: 3.78E+3nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373474(CHEMBL402769)
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373474(CHEMBL402769)
Affinity DataIC50: 450nMAssay Description:Binding affinity to human MC5RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373474(CHEMBL402769)
Affinity DataIC50: 1nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed