BDBM50373013 CHEMBL258081

SMILES Nc1ncnc2oc(c(-c3ccc(NS(=O)(=O)c4ccccc4)cc3)c12)-c1cccnc1

InChI Key InChIKey=XFTFQOAUKKRYKT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50373013   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373013(CHEMBL258081)
Affinity DataIC50: 30nMAssay Description:Inhibition of human GSK3-beta by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373013(CHEMBL258081)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of rat GSK3-beta in L6 cells assessed as accumulation of glycogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373013(CHEMBL258081)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed