BDBM50372744 CHEMBL4165080

SMILES OC(=O)c1ccc(COc2c(Cl)cc(cc2Cl)C2C3=C(CCCC3=O)NC3=C2C(=O)CCC3)cc1

InChI Key InChIKey=WMMUFXBGCRRXIW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372744   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50372744(CHEMBL4165080)
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by biotin tagged H3 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50372744(CHEMBL4165080)
Affinity DataKd:  2.62E+4nMAssay Description:Binding affinity to yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed