BDBM50372707 CHEMBL408292

SMILES Cc1ccc(cc1NC(=O)c1cnc(NCCN2CCOCC2)nc1Oc1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=WGALYVGOLFTUBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372707   

LigandPNGBDBM50372707(CHEMBL408292)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)
Affinity DataIC50: 41nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50372707(CHEMBL408292)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed