BDBM50372598 CHEMBL273041

SMILES C(CN1CCN(Cc2ccccc2)CC1)Cc1ccccc1

InChI Key InChIKey=VQEIGNPANOHOSZ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372598   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataIC50: 1.89nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in guinea pig membrane in presence of phenytoinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataIC50: 1.47nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataIC50: 100nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataIC50: 100nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H](+)-PTZ from sigma1 receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50372598(CHEMBL273041)
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed