BDBM50372518 CHEMBL257234

SMILES O=S(=O)(Nc1cccc2cccnc12)c1cccs1

InChI Key InChIKey=CPSRVVXBTZFZPM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372518   

TargetNF-kappa-B inhibitor alpha(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372518(CHEMBL257234)
Affinity DataEC50:  5.30E+3nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372518(CHEMBL257234)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNF-kappa-B inhibitor alpha(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372518(CHEMBL257234)
Affinity DataEC50:  9.00E+3nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50372518(CHEMBL257234)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed