BDBM50372508 CHEMBL256244

SMILES COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2nc(C)ccc2c1

InChI Key InChIKey=KLMFRGYXBZFEPX-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50372508   

TargetNF-kappa-B inhibitor alpha(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372508(CHEMBL256244)
Affinity DataEC50:  2.00E+4nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372508(CHEMBL256244)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNF-kappa-B inhibitor alpha(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372508(CHEMBL256244)
Affinity DataEC50:  2.00E+4nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed