BDBM50372475 CHEMBL270639

SMILES Cc1nc2cnc3ccc(cc3c2n1-c1ccc(CC#N)cc1)C#Cc1cccnc1

InChI Key InChIKey=SUCAWRZDHHYRQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372475   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372475(CHEMBL270639)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372475(CHEMBL270639)
Affinity DataIC50: 77nMAssay Description:Inhibition of phosphorylation of T308-PKB in human U87MG cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed