BDBM50372471 CHEMBL272265

SMILES N#CCc1ccc(cc1)-n1cnc2cnc3ccc(cc3c12)C#Cc1cccnc1

InChI Key InChIKey=MBIMERRBQGQJIO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50372471   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 64nMAssay Description:Inhibition of PI3K p110alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 432nMAssay Description:Inhibition of PI3K p110betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 98nMAssay Description:Inhibition of PI3K p110deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 67nMAssay Description:Inhibition of PI3K p110gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 94nMAssay Description:Inhibition of phosphorylation of T308-PKB in human U87MG cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50372471(CHEMBL272265)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed