BDBM50372165 CHEMBL402846

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cncc3n(C)nc(N)c23)c1

InChI Key InChIKey=YEPNVBNYCRGZRX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372165   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 3nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 3nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372165(CHEMBL402846)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article