BDBM50371415 CHEMBL272168

SMILES CSc1ccc(cc1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=NFDWFYUVSMRVIT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371415   

TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371415(CHEMBL272168)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371415(CHEMBL272168)
Affinity DataIC50: 64nMAssay Description:Displacement of radiolabeled MCP1 from human CCR2 in PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371415(CHEMBL272168)
Affinity DataIC50: 215nMAssay Description:Antagonist activity at human CCR2 in PBMCs assessed as inhibition of MCP1-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed