BDBM50371367 CHEMBL403594

SMILES CNC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12

InChI Key InChIKey=QCTACFWJSRSNOJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371367   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50371367(CHEMBL403594)Copy SMILESCopy InChI

Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50371367(CHEMBL403594)Copy SMILESCopy InChI

Affinity DataIC50: 66nMAssay Description:Inhibition of ebrB2 expressed in human MCF7 cells by autophosphorylation assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL