BDBM50371146 CHEMBL4168633

SMILES CC1(C)CC(=O)C2=C(C1)NC1=C(C2c2cc(Br)c(OCc3ccc(cc3)C(O)=O)c(Br)c2)C(=O)CC(C)(C)C1

InChI Key InChIKey=HDESYCKIVOTMPG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371146   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50371146(CHEMBL4168633)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50371146(CHEMBL4168633)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by biotin tagged H3 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed