BDBM50371104 CHEMBL243167

SMILES COc1ccc(CCNC(=O)c2cccc3c2[nH]c2ccccc2c3=O)cc1OC

InChI Key InChIKey=UZSASCBZXRCVQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371104   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Umr 5063 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50371104(CHEMBL243167)
Affinity DataIC50: 450nMAssay Description:Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Umr 5063 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50371104(CHEMBL243167)
Affinity DataIC50: 450nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in human HEK293 cells mediated irinotecan efflux assessed as intracellular irinotecan accumulation for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed