BDBM50370944 CHEMBL1203934

SMILES COc1cc2ncnc(Nc3ccc(F)cc3)c2cc1OC

InChI Key InChIKey=GOOMUHBHUSAARV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50370944   

TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370944(CHEMBL1203934)
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370944(CHEMBL1203934)
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed