BDBM50370942 CHEMBL1203936

SMILES COc1cc2ncnc(Nc3cc(F)cc(c3)C(F)(F)F)c2cc1OC

InChI Key InChIKey=OADSFSCZBUDKTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50370942   

TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed