BDBM50370190 CHEMBL174014

SMILES CCO[P@@](=O)(N1Cc2ccccc2C[C@H]1C(=O)NO)c1ccc(OC)cc1

InChI Key InChIKey=RBLCSCFFNCADJO-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50370190   

LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >650nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >650nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >780nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >780nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >800nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >800nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >850nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50370190(CHEMBL174014)
Affinity DataKi: >850nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed