BDBM50369822 CHEMBL1169580

SMILES CCC[C@](C)(O)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50369822   

TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataEC50:  13nMAssay Description:EC50 for binding of [35S]- GTPdeltaS in cloned human Opioid receptor delta 1 (Cl-DPDPE) transfected onto CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataEC50:  7.30nMAssay Description:EC50 for binding of [35S]- GTPdeltaS in cloned human opioid mu receptors (DAMGO) transfected onto CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataEC50:  14nMAssay Description:EC50 for binding of [35S]- GTPdeltaS in cloned human Opioid receptor kappa 1 (U-69,593) transfected onto CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against Opioid receptor delta 1 in guinea pig brain membranes using [3H]Cl-DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50369822(CHEMBL1169580)
Affinity DataKi:  2.30nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed