BDBM50369676 CHEMBL4161423

SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(SCCN(O)C(N)=O)nn1-c1ccc(Br)cc1

InChI Key InChIKey=HWKYDSTYDOMPPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50369676   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Campania "Luigi Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50369676(CHEMBL4161423)
Affinity DataIC50: 850nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Campania "Luigi Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50369676(CHEMBL4161423)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50369676(CHEMBL4161423)
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 in rat macrophages using arachidonic acid as substrate preincubated with compound for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50369676(CHEMBL4161423)
Affinity DataIC50: 850nMAssay Description:Inhibition of 5-LOX in Sprague-Dawley rat leukocytes preincubated for 30 mins followed by calcium ionophore A23187 addition and measured after 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed