BDBM50369473 CHEMBL4166048

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)Cc1ccccc1CN(CC(O)=O)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=SFWZWTSGQYFZGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50369473   

TargetNuclear factor erythroid 2-related factor 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50369473(CHEMBL4166048)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50369473(CHEMBL4166048)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of FITC-LDEETGEFL-NH2 binding to recombinant human Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia Coli BL21(DE3)pLysS c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed