BDBM50369345 CHEMBL4165724::US11207431, Example 1::US11890356, Example 1
SMILES CN(Cc1ccc(cc1F)C(=O)NO)CC23CC4CC(C2)CC(C4)C3
InChI Key InChIKey=IGZQZELTOHAHNW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 49 hits for monomerid = 50369345
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of recombinant human HDAC4 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of recombinant human HDAC5 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human HDAC6 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant human HDAC7 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human HDAC8 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC2 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC3 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC10 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:IC50 measurements were conducted by Nanosyn (Table 1A) with an established fluorescence assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 90 mins using fluorogenic substrate ZMAL (Z-Lys(Ac)-AMC) by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 90 mins using fluorogenic substrate ZMAL (Z-Lys(Ac)-AMC) by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair