BDBM50369223 CHEMBL1907788

SMILES [#6]-[#7](-[#6@H](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-1)-c1cccc(-[#7]-[#6](=O)-[#6]-[#7]-[#6](=S)-[#7]=[#6]-2-[#6]=[#6]\[#6](-[#6](=[#6]-2)-[#6](-[#8])=O)=[#6]-2\c3ccc(-[#8])cc3-[#8]-c3cc(-[#8])ccc-23)c1)-[#6](=O)-[#6]-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=HTPNBGCQAUTUAB-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50369223   

TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataIC50: 0.170nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 in electrically stimulated guinea pig longitudinal ileal muscle (GPI) preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 in electrically stimulated mouse vas deferens (MVD) preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataKi:  0.310nMAssay Description:Binding affinity towards Opioid receptor kappa 1 in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataKi:  18nMAssay Description:Binding affinity towards delta-1 opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataKi:  44nMAssay Description:Binding affinity towards delta-2 opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50369223(CHEMBL1907788)
Affinity DataKi:  286nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed