BDBM50369086 CHEMBL4162459

SMILES COc1ccc(Nc2nc(Cl)nc(Nc3ccc(cc3)N3CCOCC3=O)n2)cc1

InChI Key InChIKey=HMLAPCMRJADLSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50369086   

TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50369086(CHEMBL4162459)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid addition and measured after 2 mins by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50369086(CHEMBL4162459)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human COX2 pre-incubated for 10 mins before arachidonic acid addition and measured after 2 mins by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed