BDBM50368981 CHEMBL4168671

SMILES COc1cc(ccc1Nc1nc(N)c(s1)C(=O)c1ccc(NC(=O)C=C)cc1)N1CCN(C)CC1

InChI Key InChIKey=VYWMWKFIDRIEPP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50368981   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368981(CHEMBL4168671)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50368981(CHEMBL4168671)
Affinity DataKi:  575nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed