BDBM50367678 CHEMBL605469

SMILES CC(C)N(c1ccccc1)c1ncnc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=FOQCCKILBKXEHH-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50367678   

TargetAdenosine receptor A1(Rat)
University of Virginia School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367678(CHEMBL605469)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity to adenosine A1 receptor of rat brain membranes without NaCl by inhibition of [125-I]-labeled aminobenzyl adenosine bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50367678(CHEMBL605469)
Affinity DataEC50:  33.9nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Virginia School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367678(CHEMBL605469)
Affinity DataIC50: 430nMAssay Description:Inhibition of photolabeling of 34 kDa polypeptide in adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Virginia School of Medicine

Curated by ChEMBL
LigandPNGBDBM50367678(CHEMBL605469)
Affinity DataIC50: 1.15E+3nMAssay Description:Binding affinity towards adenosine A1 receptor of rat brain membranes with 1 M NaCl by inhibition of [125-I]-labeled aminobenzyl adenosine binding More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed