BDBM50367376 CHEMBL605866

SMILES NC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=BLMHAOGGJQDPLX-UHFFFAOYSA-N

Data  4 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50367376   

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataIC50: 70nMAssay Description:Potency against rat brain adenosine A1 receptor at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataEC50:  5.70E+3nMAssay Description:Potency against human platelet A2 adenosine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataEC50:  1.56E+3nMAssay Description:Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
Target2-oxoglutarate receptor 1(Rat)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataKi:  64nMAssay Description:Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataKi:  73nMAssay Description:Binding affinity for A1-adenosine receptor by the displacement of specific [3H]-PIA binding in rat brain was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity for recombinant rat A3-adenosine receptor by the displacement of specific [125I]APNEA or [125I]-N6-(4-amino-3-iodobenzyl)-adenosine-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50367376(CHEMBL605866)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of S-adenosyl-L-homocysteine hydrolase, inactivation rate constant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed