BDBM50366854 CHEMBL1169452

SMILES COc1cncc(c1)C#Cc1ccccn1

InChI Key InChIKey=VRTFKUFTEWQHDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50366854   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366854(CHEMBL1169452)
Affinity DataIC50: 12nMAssay Description:Binding affinity towards mGlu5 receptors in rat brain membranes was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366854(CHEMBL1169452)
Affinity DataIC50: 1nMAssay Description:In vitro functional potency using an automated assay employing LtK-cells stably expressing human recombinant mGlu5 receptor by measuring changes in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed