BDBM50366628 CHEMBL4165574

SMILES N[C@@H]([C@H](OCC1CCCC1)C(O)=O)C(O)=O

InChI Key InChIKey=RKVSHHVBUFXVQV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366628   

TargetExcitatory amino acid transporter 4(Rat)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 4(Rat)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 940nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50366628(CHEMBL4165574)
Affinity DataIC50: 933nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed