BDBM50366492 DAMNACANTHAL

SMILES COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12

InChI Key InChIKey=IPDMWUNUULAXLU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366492   

TargetTyrosine-protein kinase Lck(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 620nMAssay Description:Inhibition of p56lck-mediated exogenous peptide phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 800nMAssay Description:Inhibition of Limk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 17nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 17nMAssay Description:Inhibition of p56lck autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 800nMAssay Description:Inhibition of his6 tagged LIMK1 (unknown origin) expressed in baculovirus-infected Sf9 cells measured after 1 hr in presence of ATP by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of his6 tagged LIMK2 (unknown origin) expressed in baculovirus-infected Sf9 cells measured after 1 hr in presence of ATP by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 800nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50366492(DAMNACANTHAL)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of LIMK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed