BDBM50366292 Dehydroroemerine

SMILES CN1CCc2cc3OCOc3c3c4ccccc4cc1c23

InChI Key InChIKey=YUWBTKIVDAWQHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50366292   

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50366292(Dehydroroemerine)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Net1 (149 to 501 residues) (unknown origin) interaction with GDP-loaded His-tagged RhoA F25N mutant (1 to 180 residues) assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50366292(Dehydroroemerine)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50366292(Dehydroroemerine)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed