BDBM50365795 CHEMBL1956574

SMILES O=C1NCc2cc(ccc12)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12

InChI Key InChIKey=PMFMZQFBDGJDMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365795   

TargetMAP kinase-activated protein kinase 5(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365795(CHEMBL1956574)
Affinity DataIC50: 239nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365795(CHEMBL1956574)
Affinity DataIC50: 676nMAssay Description:Inhibition of MAPKAPK5 in synovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed