BDBM50365612 CHEMBL1957960

SMILES Oc1ccc(C(=O)NCCCn2cnc(Cl)c2Cl)c2[nH]c(nc12)-c1ccco1

InChI Key InChIKey=HGSDLYGGJSEMFM-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365612   

TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365612(CHEMBL1957960)
Affinity DataEC50:  40nMAssay Description:Inhibition of GSK3-beta in human RD cells assessed as glycogen synthase activation measured after 24 hrs under serum starving conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365612(CHEMBL1957960)
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365612(CHEMBL1957960)
Affinity DataEC50:  50nMAssay Description:Inhibition of GSK3-beta in human RD cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed