BDBM50365606 CHEMBL1957953

SMILES OC(=O)COc1cccc(CCCNC(=O)c2ccc(O)c3nc([nH]c23)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=VBXXIIUXGXMRCJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365606   

TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365606(CHEMBL1957953)
Affinity DataIC50: 31nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365606(CHEMBL1957953)
Affinity DataEC50:  80nMAssay Description:Inhibition of GSK3-beta in human RD cells assessed as glycogen synthase activation measured after 24 hrs under serum starving conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Crystalgenomics

Curated by ChEMBL
LigandPNGBDBM50365606(CHEMBL1957953)
Affinity DataEC50:  250nMAssay Description:Inhibition of GSK3-beta in human RD cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed