BDBM50365515 CHEMBL1957506

SMILES CN(C)CCNC(=O)c1cn2cc(nc(N3CCOCC3)c2n1)-c1cccc2[nH]ncc12

InChI Key InChIKey=PKDDPYVEJSWSNT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365515   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL

LigandBDBM50365515(CHEMBL1957506)Copy SMILESCopy InChI

Affinity DataEC50:  976nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL

LigandBDBM50365515(CHEMBL1957506)Copy SMILESCopy InChI

Affinity DataIC50: 35nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL