BDBM50365451 CHEMBL1957253

SMILES Clc1ccc(NC(=O)Cn2c(nc3ccccc23)-c2cncs2)cc1

InChI Key InChIKey=PWNZHWBKHSCYQV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365451   

TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50365451(CHEMBL1957253)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50365451(CHEMBL1957253)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50365451(CHEMBL1957253)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2013
Entry Details Article
PubMed