BDBM50365396 CHEMBL1956397

SMILES NC(=O)CS(=O)Cc1ccccc1-c1ccc(Cl)cc1

InChI Key InChIKey=NGKMIRWLVJBBBI-UHFFFAOYSA-N

Data  23 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50365396   

TargetTransporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat NET-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 600nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 830nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent serotonin transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of CYP2C9 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of CYP2D6 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 3A5(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of CYP3A5 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of CYP3A4 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of CYP2C19 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent serotonin transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of rat SERT-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 600nMAssay Description:Inhibition of rat DAT-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of CYP2C9 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of CYP2D6 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 3A5(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of CYP3A5 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of CYP3A4 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of CYP2C19 in human microsomeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent serotonin transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of rat SERT-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat NET-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium-dependent dopamine transporter(Rat)
Cephalon

Curated by ChEMBL

LigandBDBM50365396(CHEMBL1956397)Copy SMILESCopy InChI

Affinity DataIC50: 600nMAssay Description:Inhibition of rat DAT-mediated uptakeMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL