BDBM50365330 CHEMBL1956107

SMILES CN[C@H]1CC[C@H](CC1)N1CCc2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=HGVUTNMCDMGTOE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50365330   

TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of human recombinant eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 4.40E+3nMAssay Description:Displacement of [3H]nisoxetine from human recombinant norepinephrine transporter expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of rat recombinant eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of rat recombinant iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]L-arginine to [3H]L-citrulline in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365330(CHEMBL1956107)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human Erg expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed