BDBM50365167 CHEMBL1950019

SMILES CCc1cc(ncc1Cl)C(=O)c1[nH]c2cc(Cl)ccc2c1CC(O)=O

InChI Key InChIKey=GRTNJTOOCDMMEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365167   

TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365167(CHEMBL1950019)
Affinity DataIC50: 31nMAssay Description:Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365167(CHEMBL1950019)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed