BDBM50365124 CHEMBL1952408

SMILES CN1CC(C)(COc2ccc(cc2)C(N)=N)Oc2cc(ccc12)N(CC(O)=O)Cc1ccc(F)c(F)c1

InChI Key InChIKey=SZWPVMQKXNYKOT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50365124   

TargetIntegrin alpha-IIb/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365124(CHEMBL1952408)
Affinity DataIC50: 8.00E+4nMAssay Description:Displacement of biotinylated fibrinogen from human alpha2b-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365124(CHEMBL1952408)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of biotinylated fibrinogen from human alpha5-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365124(CHEMBL1952408)
Affinity DataKi:  810nMAssay Description:Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365124(CHEMBL1952408)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of factor 10a using S-2222 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed